Increase in dermcidin-derived peptides in sweat of patients with atopic eczema caused by a humorous video
Increase in dermcidin-derived peptides in sweat of patients with atopic eczema caused by a humorous video
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DOI：
10.1016/j.jpsychores.2006.05.006
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发表时间：
2007-01-01
影响因子：
4.7
通讯作者：
Kimata, Hajime
中科院分区：
文献类型：
--
作者：
Kimata, Hajime
目的：Dermcidin (DCD) 衍生肽是一种由汗腺产生的抗菌肽。然而，特应性湿疹 (AE) 患者汗液中 DCD 衍生肽的水平降低。研究了观看幽默视频对 DCD 衍生肽水平的影响。方法：20 名 AE 患者观看了一段 87 分钟的幽默视频（《现代时报》，由查理·卓别林主演）。在观看之前和观看之后立即收集汗液，并测量汗液中的DCD衍生肽和总蛋白的水平。结果：观看幽默视频会增加 DCD 衍生肽的水平，但不会影响汗液中总蛋白的水平。结论：观看幽默视频可增加AE患者汗液中的DCD衍生肽，因此可能有助于治疗AE皮肤感染。 (c) 2007 Elsevier Inc. 保留所有权利。
Objective: Dermcidin (DCD)-derived peptide is an antimicrobial peptide produced by the sweat glands. However, the levels of DCD-derived peptide in sweat were decreased in patients with atopic eczema (AE). The effect of viewing a humorous video on the levels of DCD-derived peptide was studied. Methods: Twenty patients with AE viewed an 87-min humorous video (Modem Times, featuring Charlie Chaplin). Just before and immediately after viewing, sweat was collected, and the levels of DCD-derived peptide and total protein in sweat were measured. Results: Viewing a humorous video increased the levels of DCD-derived peptide without affecting the levels of total protein in sweat. Conclusion: Viewing a humorous video increased DCD-derived peptide in sweat of patients with AE, and thus, it may be helpful in the treatment of skin infection of AE. (c) 2007 Elsevier Inc. All rights reserved.