SCALP DISTRIBUTION OF HUMAN AUDITORY EVOKED-POTENTIALS .2. EVIDENCE FOR OVERLAPPING SOURCES AND INVOLVEMENT OF AUDITORY-CORTEX
SCALP DISTRIBUTION OF HUMAN AUDITORY EVOKED-POTENTIALS .2. EVIDENCE FOR OVERLAPPING SOURCES AND INVOLVEMENT OF AUDITORY-CORTEX
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DOI：
10.1016/0013-4694(82)90228-0
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发表时间：
1982-01-01
期刊：
影响因子：
--
通讯作者：
WOLPAW, JR
中科院分区：
文献类型：
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作者：
WOOD, CC;WOLPAW, JR
本文采用非头侧参考记录法研究了20-250 ms的听觉诱发电位（AEP）的头皮分布。在11名受试者的右半球20个头皮位置同时记录双耳短声刺激的AEP。计算机生成的高时间分辨率等电压地形图被用来评估AEP头皮分布随时间的稳定性，并将它们与AEP波形中的主峰相关联。对于20-60 ms的电位，结果显示了稳定的头皮分布的偶极形式，这与颞顶交界处附近的上级颞平面上的初级听觉皮层中的源一致。对于60-250 ms的电位，结果显示了电极位置上AEP形态的变化和头皮分布随时间的变化，得出了2个主要结论。首先，在这个潜伏期内的AEP是由多个源产生的，这些源在时间上部分重叠。第二，听觉皮层的一个或多个区域在这一时期对AEP有重要贡献。需要额外的数据来确定听觉皮层源在上级颞平面和侧颞表面上的相对贡献，并识别颞叶外的AEP源。
The scalp distributions of human auditory evoked potentials (AEP) between 20-250 ms were investigated using noncephalic reference recordings. AEP to binaural click stimuli were recorded simultaneously from 20 scalp locations over the right hemisphere in 11 subjects. Computer-generated isovoltage topographic maps at high temporal resolution were used to assess the stability of AEP scalp distributions over time and relate them to major peaks in the AEP wave forms. For potentials from 20-60 ms, the results show a stable scalp distribution of dipolar form that is consistent with sources in primary auditory cortex on the superior temporal plane near the temporoparietal junction. For potentials from 60-250 ms, the results show changes in AEP morphology across electrode locations and changes in scalp distribution over time that lead to 2 major conclusions. First, AEP in this latency period are generated by multiple sources which partially overlap in time. Second, one or more regions of auditory cortex contribute significantly to AEP in this period. Additional data are needed to determine the relative contribution of auditory cortex sources on the superior temporal plane and the lateral temporal surface and to identify AEP sources outside the temporal lobe.