Superchiral fields generated by nanostructures and their applications for chiral sensing
Superchiral fields generated by nanostructures and their applications for chiral sensing
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纳米结构产生的超手性场及其在手性传感中的应用
DOI：
10.1088/1674-1056/ac11df
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Zhang Xiangdong
中科院分区：
文献类型：
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作者：
Zhang Huizhen;Zhang Weixuan;Hou Saisai;Wang Rongyao;Zhang Xiangdong
手性在自然界是普遍存在的。手性对映体虽然具有相似的理化性质，但在生物化学过程中发挥的作用不同。手性对映体的鉴别在生化、分析化学和制药工业中具有极其重要的意义。由于天然手性分子的信号微弱，传统的手性光谱方法在检测灵敏度有限的情况下是不利的。近年来，超手性场被提出来有效地增强光与分子之间的相互作用，从而实现超灵敏的手性检测。基于人工纳米结构的超手性场的产生及其在超灵敏手性传感中的应用已经得到了大量的理论和实验研究。在这篇综述中，我们对这些工作进行了综述。我们从介绍电磁场的手性开始。然后，分别讨论了基于手性和非手性纳米结构的光学手性增强和超灵敏手性检测。最后，对超灵敏手性传感技术进行了总结和展望。
Chirality is ubiquitous in natural world. Although with similar physical and chemical properties, chiral enantiomers could play different roles in biochemical processes. Discrimination of chiral enantiomers is extremely important in biochemical, analytical chemistry, and pharmaceutical industries. Conventional chiroptical spectroscopic methods are disadvantageous at a limited detection sensitivity because of the weak signals of natural chiral molecules. Recently, superchiral fields were proposed to effectively enhance the interaction between light and molecules, allowing for ultrasensitive chiral detection. Intensive theoretical and experimental works have been devoted to generation of superchiral fields based on artificial nanostructures and their application in ultrasensitive chiral sensing. In this review, we present a survey on these works. We begin with the introduction of chiral properties of electromagnetic fields. Then, the optical chirality enhancement and ultrasensitive chiral detection based on chiral and achiral nanostructures are discussed respectively. Finally, we give a short summary and a perspective for the future ultrasensitive chiral sensing.