Sex-Related Differences in Locomotion and Climbing of C57Bl/6NTac Mice in a Novel Environment
Sex-Related Differences in Locomotion and Climbing of C57Bl/6NTac Mice in a Novel Environment
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DOI：
10.33549/physiolres.934348
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发表时间：
2019-01-01
影响因子：
2.1
通讯作者：
Riljak, V
中科院分区：
文献类型：
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作者：
Borbelyova, V;Janisova, K.;Riljak, V
实验小鼠在标准实验室笼中，除了水平和垂直运动活动外，自发地表现出与笼栏相关的活动，如爬笼格。虽然爬网活动是小鼠自发家笼行为的主要组成部分之一，但其确切作用尚不完全清楚。本研究旨在描述实验室小鼠在观察者独立的野外爬笼活动中应对新奇事物和自发行为的性别差异。采用labas系统对成年小鼠（C57Bl/6NTac）进行行为学测试。雌性小鼠行走的距离明显更长(30%,p
Laboratory mice in standard laboratory cages, besides horizontal and vertical locomotor activity, spontaneously display cage-bar related activities such as cage-grid climbing. Although, gridclimbing activity is one of the major components of spontaneous home-cage behavior of mice, its exact role is not fully understood. This study aimed to describe the sex-differences in coping with novelty and in spontaneous behavior of laboratory mice concerning the cage-climbing activity in an observer-independent open field test. Adult mice of both sexes (C57Bl/6NTac) underwent behavioral testing in LABORAS system. Female mice travelled significantly longer distance (by 30 %, p