Outbreak of infection by carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-58 in Belgium
Outbreak of infection by carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-58 in Belgium
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DOI：
10.1128/jcm.00796-06
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发表时间：
2006-11-01
影响因子：
9.4
通讯作者：
Glupczynski, Youri
中科院分区：
文献类型：
--
作者：
Bogaerts, Pierre;Naas, Thierry;Glupczynski, Youri
碳青霉烯类耐药鲍曼不动杆菌分离株是从2004年9月至2005年8月期间在Academisch Ziekenhuis Vrije Universiteit Bensel（布鲁塞尔，比利时）的17名患者中获得的。这些多重耐药分离株属于单一克隆，仅对粘菌素和替加环素敏感，并产生碳青霉烯水解苯唑西林酶OXA-58。这项研究强调了这种β-内酰胺酶介导的耐药机制及其流行演变的国家间传播的重要性。
Carbapenem-resistant Acinetobacter baumannii isolates were obtained from 17 patients between September 2004 and August 2005 at the Academisch Ziekenhuis Vrije Universiteit Brussel, Brussels, Belgium. These multidrug-resistant isolates, which belonged to a single clone, remained susceptible to colistin and tigecycline only and produced the carbapenem-hydrolyzing oxacillinase OXA-58. This study highlights the importance of the intercountry spread of this P-lactamase-mediated resistance mechanism and its epidemic evolution.