Design and Scaling Up of Microchemical Systems: A Review.
Design and Scaling Up of Microchemical Systems: A Review.
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DOI：
10.1146/annurev-chembioeng-060816-101443
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发表时间：
2017-06
影响因子：
8.4
通讯作者：
Jisong Zhang;Kai Wang;Andrew R. Teixeira;K. Jensen;G. Luo
中科院分区：
文献类型：
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作者：
Jisong Zhang;Kai Wang;Andrew R. Teixeira;K. Jensen;G. Luo
近二十年来，微反应器得到了迅速的发展。大量的反应已经在微化学系统中进行了测试，揭示了控制停留时间，提高运输效率，高产品收率和固有安全性的优点。本文介绍了微化学系统的定义、组成和应用以及微混合器的基本结构。我们专注于混合，流动动力学，质量和热量传递在微反应器沿着与三种策略按比例放大微反应器：并行编号，连续编号，和按比例放大。我们还提出了一种可能的方法来设计微化学系统。最后对本文进行了总结和展望。
The past two decades have witnessed a rapid development of microreactors. A substantial number of reactions have been tested in microchemical systems, revealing the advantages of controlled residence time, enhanced transport efficiency, high product yield, and inherent safety. This review defines the microchemical system and describes its components and applications as well as the basic structures of micromixers. We focus on mixing, flow dynamics, and mass and heat transfer in microreactors along with three strategies for scaling up microreactors: parallel numbering-up, consecutive numbering-up, and scale-out. We also propose a possible methodology to design microchemical systems. Finally, we provide a summary and future prospects.