IGF-I, IGFBP-3, and IGF-I/IGFBP-3 ratio: no association with incident colorectal cancer in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study.

IGF-I, IGFBP-3, and IGF-I/IGFBP-3 ratio: no association with incident colorectal cancer in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study.
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IGF-I、IGFBP-3 和 IGF-I/IGFBP-3 比率:在α-生育酚、β-胡萝卜素癌症预防研究中与结直肠癌的发生没有关联。

DOI:
10.1158/1055-9965.epi-08-0345
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发表时间:
2008
期刊:
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子:
--
通讯作者:
Albanes,Demetrius
Albanes,Demetrius
中科院分区:
--
文献类型:
--
作者:
Max,JoshuaB;Limburg,PaulJ;Ogunseitan,Adeboye;Stolzenberg-Solomon,RachaelZ;Vierkant,RobertA;Pollak,MichaelJ;Sellers,ThomasA;Virtamo,Jarmo;Cerhan,JamesR;Albanes,Demetrius

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Materials and MethodsThe design and conduct of the Alpha-Tocopherol, Beta-Carotene Study have been reported (5). In brief, 29,133 male cigarette smokers, ages 50 to 69 years, living in southwestern Finland with no previous cancer diagnosis were recruited between 1985 and 1988 and provided fasting serum samples that were archived at− 70 C. Demographic, anthropometric, and exposure data were collected using self-reported questionnaires and focused physical examination. Incident cancer cases were identified through the Finnish Cancer Registry, which provides nearly 100% case ascertainment (6).