Population-Based Prevalence of Intellectual Disability and Autism Spectrum Disorders in Western Australia: A Comparison With Previous Estimates.
Population-Based Prevalence of Intellectual Disability and Autism Spectrum Disorders in Western Australia: A Comparison With Previous Estimates.
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DOI：
10.1097/md.0000000000003737
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发表时间：
2016-05
期刊：
影响因子：
1.6
通讯作者：
Leonard H
中科院分区：
文献类型：
--
作者：
Bourke J;de Klerk N;Smith T;Leonard H
调查西澳大利亚州（WA）智力残疾（ID）和/或自闭症谱系障碍（ASD）的患病率。使用基于人口的IDEA（智力残疾探索答案）数据库确定了1983年至2010年在西澳出生的ID和/或ASD儿童的队列，该数据库通过残疾服务委员会（DSC）以及教育来源收集病例。通过与助产士通知系统和死亡登记册的连接，获得了关于种族、性别、出生时母亲居住地和死亡的信息。通过审查可用的医疗记录获得ID原因的诊断信息，并将儿童分类为生物医学原因、ASD或未知原因。ID的总体患病率为17.0/1000例活产（95% CI：16.7，17.4），与10年前的患病率14.3/1000相比有所增加。轻度或中度ID的患病率为15.0（95% CI：14.6，15.3），重度ID为1.2（95% CI：1.1，1.3），ID水平未知为0.9（95% CI：0.8，1.0）/1000例活产。土著儿童的患病率为39.0/1 000，而非土著儿童为15.7/1 000，患病率为2.5（95%置信区间：2.4，2.6）。所有ASD的患病率为5.1/1000，其中3.8/1000患有ASD和ID。ID的患病率在过去10年中在WA有所上升，其中大部分是由于轻度或中度ID。虽然ASD的患病率在这段时间也有所增加，但这并不能完全解释观察到的增加。原住民儿童患ID的风险是其他儿童的2.5倍，但获得残疾服务的可能性较小。
To investigate the prevalence of intellectual disability (ID) and/or autism spectrum disorders (ASDs) in Western Australia (WA). A cohort of children born from 1983 to 2010 in WA with an ID and/or ASD were identified using the population-based IDEA (Intellectual Disability Exploring Answers) database, which ascertains cases through the Disability Services Commission (DSC) as well as education sources. Information on race, gender, mother's residence at birth and deaths was obtained through linkage to the Midwives Notification System and the Mortality Register. Diagnostic information on the cause of ID was obtained through review of medical records where available and children were classified as biomedical cause, ASD, or unknown cause. An overall prevalence of ID of 17.0/1000 livebirths (95% CI: 16.7, 17.4) showed an increase from the 10-year previous prevalence of 14.3/1000. The prevalence for mild or moderate ID was 15.0 (95% CI: 14.6, 15.3), severe ID was 1.2 (95% CI: 1.1, 1.3), and unknown level of ID was 0.9 (95% CI: 0.8, 1.0)/1000 livebirths. The prevalence for Aboriginal children was 39.0/1000 compared with 15.7/1000 for non-Aboriginal children, giving a prevalence ratio of 2.5 (95% CI: 2.4, 2.6). Prevalence of all ASD was 5.1/1000 of which 3.8/1000 had ASD and ID. The prevalence of ID has risen in WA over the last 10 years with most of this increase due to mild or moderate ID. Whilst the prevalence of ASD has also increased over this time this does not fully explain the observed increase. Aboriginal children are at a 2.5-fold risk of ID but are less likely to be accessing disability services.