The human brain propose the development of new concept of brain hypothermia treatment
The human brain propose the development of new concept of brain hypothermia treatment
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人类大脑提出开发脑低温治疗新理念
DOI：
--
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
N. Hayashi
中科院分区：
文献类型：
--
作者：
N. Hayashi
当中风、外伤和心脏骤停造成严重脑损伤时，人类大脑需要情绪、思维和心智的神经元恢复。然而，情感、思维、心智的产生机制以及这些神经元功能障碍的管理护理方法尚未得到精确论证。长期以来，我们一直致力于外在刺激反应意识的恢复；通过控制脑水肿、ICP（颅内压）升高和 CBF（脑血流）紊乱来控制外意识，如格拉斯哥昏迷量表所示。然而，人类意识不仅对外部刺激做出反应，还对内部意识（并不总是必要的外部刺激）做出反应，例如情感、思维和心灵。这可能是因为在严重的 TBI（创伤性脑损伤）和 CPA（心肺骤停）患者中，先前的神经保护管理和诱导脑低温治疗的临床管理存在特定的陷阱。以往的脑低温处理方法对于预防急性期思维、记忆、情绪损害的具体考虑还不够。本文讨论了人脑产生情感、思维、记忆和心智的机制，并提出了动态中心核心（DCC）功能的新概念，它与额叶、纹状体基底神经节、A10神经系统、丘脑、海马体和边缘系统联合产生内在意识。因此，成功的脑低温治疗对于情绪、思维和心智的神经元恢复还应该关注更多的内在意识神经元功能，例如通过多神经元放电形成一个明确的神经元概念，以及通过 DCC 中的 synfire（神经放电同步）将情绪从人脑转移到另一个人脑。神经元低温（JJAAM.
The human The human brain requests the neuronal recovery of emotions, thinking and mind when the fall in severe brain damage by stroke, trauma, and cardiac arrest. However, the mechanism of production of emotion, thinking, and mind and also the management care method of these neuronal dysfunctions were not demonstrated, precisely. We have been focused on, for long time, the recovery of outer stimulation responding consciousness; outer consciousness as shown as Glasgow Coma Scale by control of brain edema, ICP (intracranial pressure) elevation, and CBF (cerebral blood flow) disturbances. However, human consciousness response to not only for outer stimulation and also for inner consciousness (not always necessary outer stimulation) such as emotion, thinking, and mind. This maybe be-cause there are specific pitfalls associated with the clinical management of previous neuro-protection management and also induced brain hypothermia treatment, in severe TBI (traumatic brain injury) & CPA (cardiopulmonary arrest) patients. The previous brain hypothermia management method is not enough for specific consideration about preventing of damage of thinking, memory, and emotions from acute stage. In this paper, the mechanism of production of emotion, thinking, memory and mind in the human brain have been discussed and presented new concept of Dynamic Center Core (DCC) function that works with union of frontal lobe, striatum-basal ganglia, A10-nerve system, thalamus, hippocampus, and limbic system for producing inner consciousness. Therefore, the successful brain hypothermia treatment for neuronal recovery of emotion, thinking, and mind should be also focused on much more inner consciousness neuronal function such as one definite neuronal concept formation from multi-neuronal firing and also emotional translation from human brain to another human brain by synfire (synchronization of neural firing) in DCC. neuronal hypothermia (JJAAM.
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影响因子：
158.5
作者：
Clifton, GL;Miller, ER;Schwartz, M
通讯作者：
Schwartz, M
影响因子：
4.1
作者：
SHEINBERG, M;KANTER, MJ;GROSSMAN, RG
通讯作者：
GROSSMAN, RG
羟基自由基对多巴胺的攻击。
DOI：
--
发表时间：
1985
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Slivka,A;Cohen,G
通讯作者：
Cohen,G
DOI：
10.1097/01.nt.0000369548.36707.50
发表时间：
2010-05
期刊：
The New England journal of medicine
影响因子：
--
作者：
Fang Sun;Guoqing Zhou
通讯作者：
Fang Sun;Guoqing Zhou
神经外科患者脑代谢和底物输送的多参数连续监测。
影响因子：
1.9
作者：
Zauner,A;Doppenberg,E;Woodward,JJ;Allen,C;Jebraili,S;Young,HF;Bullock,R
通讯作者：
Bullock,R