FIBRILLATION IN SKELETAL MUSCLE IN RELATION TO DENERVATION AND TO INACTIVATION WITHOUT DENERVATION
FIBRILLATION IN SKELETAL MUSCLE IN RELATION TO DENERVATION AND TO INACTIVATION WITHOUT DENERVATION
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与去神经支配和不去神经支配的失活相关的骨骼肌颤动
DOI：
10.1152/jn.1941.4.5.398
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发表时间：
1941
期刊：
影响因子：
--
通讯作者：
D. Bodian
中科院分区：
文献类型：
--
作者：
S. S. Tower;H. Howe;D. Bodian
为了研究外科手术将脊髓与所有进入的神经冲动隔离可能构成依赖性骨骼肌的功能性去神经支配，从而使其进入纤维性颤动的可能性，在两只猴子身上分离了脊髓的腰骶区，此外，在每只猴子身上切割了一条坐骨神经。两周后，暴露两侧腿部肌肉，检查是否有纤维性颤动。仍然控制着神经支配的肌肉是静止的，没有颤动；但是肌肉失神经是由坐骨部分造成的，或者在一只动物身上，是由于孤立的脊髓部分完全退化造成的。Ent，被发现是颤动的，并且比静止的肌肉颜色更深。结论是：
To investigate the possibility that surgical isolation of the spinal cord from all ingoing nerve impulses might constitute a functional denervation of the dependent skeletal muscle such that this enters into fibrillation, the lumbo-sacral region of cord was so isolated in two monkeys and in addition, one sciatic nerve was cut in each. Two weeks thereafter leg muscles were exposed on the two sides and examined for fibrillation. Muscle still in possession of its innervation was found to be at rest, not fibrillating; but muscle denervated either by sciatic section, or, in one animal, in consequence of complete degeneration of the isolated cord segm. ent, was found to be fibrillating and of a deeper red color than the muscle at rest. It is concluded,