EVALUATION OF THE HISTOPATHOLOGICAL CLASSIFICATIONS OF AMERICAN CUTANEOUS AND MUCOCUTANEOUS LEISHMANIASIS

EVALUATION OF THE HISTOPATHOLOGICAL CLASSIFICATIONS OF AMERICAN CUTANEOUS AND MUCOCUTANEOUS LEISHMANIASIS
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DOI:
10.1590/s0074-02761991000100009
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发表时间:
1991-01-01
影响因子:
2.8
通讯作者:
BARRAL, A
BARRAL, A
中科院分区:
医学4区
文献类型:
--
作者:
BITTENCOURT, AL;BARRAL, A

文献摘要

被引文献

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为了评价皮肤和粘膜皮肤利什曼病组织病理学分类的可靠性,作者比较了同一患者同时进行的两次活检的组织病理学模式,并根据Ridley等人(1980)、Magalhaes等人(1986 a)和仅具有三种模式的更简化的分类对材料进行了分类。在不同的病变或甚至在同一病变中观察到不同的组织病理学方面。作者得出结论,组织病理学模式并不代表表皮利什曼病的一个阶段,因此它们不能与文献中提出的预后和治疗反应相关。
In order to evaluate the reliability of histopathological classifications of cutaneous and mucocutaneous leishmaniasis the authors compared the histopathological patterns of two biopsies taken simultaneously from the same patient, and classified the material according to Ridley et al. (1980), to Magalhaes et al. (1986a), and to a more simplified classification with only three patterns. Distinct histopathological aspects were observed in different lesions or even in the same lesion. The authors concluded that histopathological patterns do not represent a stage of tegumentary leishmaniasis, thus they can not be correlated with prognosis and therapeutical response as suggested in the literature.