Response to motion in extrastriate area MST1: Center-surround interactions
Response to motion in extrastriate area MST1: Center-surround interactions
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DOI：
10.1152/jn.1998.80.1.282
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发表时间：
1998-07-01
影响因子：
2.5
通讯作者：
Wurtz, RH
中科院分区：
文献类型：
--
作者：
Eifuku, S;Wurtz, RH
猕猴纹外视皮层内侧上级颞区可分为背内侧区（MSTd）和外侧腹侧区（MSTl）。这两个区域的功能可能不相同：MSTd可以处理由观察者的运动产生的光流信息，而MSTl可以更紧密地与处理与对象的运动具体相关的视觉运动相关。如果MST1与这样的物体运动有关，人们将期望看到用于将物体从其周围分离的机制。我们研究了MST1神经元中的这些机制之一：落在感受野中心周围区域的刺激对落在场中心的刺激的反应的影响。我们发现，周围刺激的影响是调制与周围刺激本身的反应很小，但一个明确的影响，对刺激的反应落在感受野中心。当周围运动的方向与中心运动的方向相反时，神经元对中心运动的反应通常会增加，而当周围运动的方向与中心运动的方向相同时，反应会减少。57%的神经元对中心运动的反应与对中心运动的反应之比> 1。当周围刺激静止时，中心运动的反应也增加，这种增加有时比周围运动时更大。近70%的神经元显示出对具有静止周围的中心运动的响应与仅对中心运动的响应的比率>1。这与中颞区神经元中静止环绕物的最小影响相反。当刺激呈现被反转，使得中心的刺激是静止的而周围移动时，当周围的运动方向与感受野中心的优选运动方向相反时，一些MST1神经元做出反应。因此，刺激周围的MST 1神经元的反应产生了深远的影响，这种显着的效果的周围是一致的分割对象中使用的运动的作用。
The medial superior temporal area of the macaque monkey extrastriate visual cortex can be divided into a dorsal medial (MSTd) and a lateral ventral (MSTl) region. The functions of the two regions may not be identical: MSTd may process optic flow information that results from the movement of the observer, whereas MSTl may be related more closely to processing visual motion related specifically to the motion of objects. If MSTl were related to such object motion, one would expect to see mechanisms for the segregation of objects from their surround. We investigated one of these mechanisms in MSTl neurons: the effect of stimuli falling in the region surrounding the receptive field center on the response to stimuli falling in the field center. We found the effects of the surround stimulation to be modulatory with little response to the surround stimulus itself but a clear effect on the response to the stimulus falling on the receptive field center. The response to motion in the center in the direction preferred for the neuron usually increased when the surround motion was in the opposite direction to that in the center and decreased when surround motion was in the same direction as that in the center. Fifty-seven percent of the neurons showed a ratio of response for center motion with a surround moving in the opposite direction to that in the center for center motion alone that was >1.The response to motion in the center also increased when the surround stimulus was stationary, and this increase was sometimes larger than that with a moving surround. Nearly 70% of the neurons showed a ratio of response to center motion with a stationary surround to center motion alone that was >1. This is in contrast to the minimal effect of stationary surrounds in middle temporal area neurons. When the stimulus presentation was reversed so that the stimulus in the center was stationary and the surround moved, some MSTl neurons responded when the direction of motion in the surround was in the direction opposite to the preferred direction of motion in the center of the receptive field. Stimulation of the surround thus had a profound effect on the response of MST1 neurons, and this pronounced effect of the surround is consistent with a role in the segmentation of objects using motion.