Clinician-assisted Internet-based treatment is effective for depression: Randomized controlled trial

Clinician-assisted Internet-based treatment is effective for depression: Randomized controlled trial
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DOI:
10.1080/00048670902873722
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发表时间:
2009-01-01
影响因子:
4.6
通讯作者:
Andrews, Gavin
Andrews, Gavin
中科院分区:
医学2区
文献类型:
--
作者:
Perini, Sarah;Titov, Nickolai;Andrews, Gavin

文献摘要

被引文献

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目的:本研究的目的是确定基于互联网的临床医生辅助的计算机化认知行为治疗(CaCCBT)方案对抑郁症的疗效。方法:45名符合抑郁症诊断标准的人被随机分配到悲伤计划或等待名单对照组。在临床医生辅助的悲伤计划中,参与者完成六节在线课程,每周完成家庭作业,每周收到临床心理学家的电子邮件联系,并与其他参与者一起参与主持的在线讨论论坛。数据分析采用意向处理模型。结果:共有20名(74%)治疗组参与者在8周的计划内完成了所有课程,治疗后数据收集自18/27名治疗组和17/18名等待名单组参与者。根据贝克抑郁问卷第二版和患者健康问卷九项的测量,治疗组参与者报告抑郁症状显著减少。治疗组参与者每人平均收到8封电子邮件联系(111分钟的治疗师时间)。两种抑郁症状测量的组内和组间平均效应大小(Cohen‘s d)分别为0.98和0.75。与会者认为治疗方案是可以接受和满意的。结论:这些结果重复了Perini等人报道的先导试验的结果。并与文献一致,表明基于互联网的抑郁症和其他精神障碍方案与临床指导相结合可以导致临床上的显著改善。这些数据为基于互联网的常见精神障碍治疗的发展提供了进一步的支持。
Objective: The aim of the present study was to determine the efficacy of an Internet-based clinician-assisted computerized cognitive behavioural treatment (CaCCBT) programme for depression. Method: Forty-five individuals meeting diagnostic criteria for depression were randomly assigned to the Sadness programme or to a waitlist control group. In the clinician-assisted Sadness programme, participants complete six online lessons, weekly homework assignments, receive weekly email contact from a clinical psychologist, and contribute to a moderated online discussion forum with other participants. An intention-to-treat model was used for data analyses. Results: A total of 20 (74%) treatment group participants completed all lessons within the 8 week programme, and post-treatment data were collected from 18/27 treatment group and 17/18 waitlist group participants. Treatment group participants reported significantly reduced symptoms of depression as measured by the Beck Depression Inventory-second edition and the Patient Health Questionnaire-Nine Item. Treatment group participants each received an average of eight email contacts (111 min of therapist time]. Mean within- and between-group effect sizes (Cohen's d) across the two measures of depressive symptoms were 0.98 and 0.75, respectively. Participants found the treatment programme acceptable and satisfactory. Conclusions: These results replicate those from the pilot trial reported by Perini et al. and are consistent with literature indicating that Internet-based programmes for depression and other mental disorders combined with clinical guidance can result in clinically significant improvements. These data provide further support for the development of Internet-based treatment for common mental disorders.