Trophic and maternal transfer of selenium in brown house snakes (Lamprophis fuliginosus)
Trophic and maternal transfer of selenium in brown house snakes (Lamprophis fuliginosus)
复制标题
DOI：
10.1016/s0147-6513(03)00076-9
复制
发表时间：
2004-07-01
影响因子：
6.8
通讯作者：
Ford, NB
中科院分区：
文献类型：
--
作者：
Hopkins, WA;Staub, BP;Ford, NB
食物中过量的硒对卵生脊椎动物(即鱼类和鸟类)是有毒的，但对其在爬行动物中的积累和影响知之甚少。我们通过在雌性褐家蛇的猎物中注射硒-D，L-蛋氨酸，将雌性褐家蛇暴露在10和20毫克/克的硒中，并将这些蛇与背景水平类似于1杯/克膳食硒的个体进行比较。蛇被喂以相当于其体重25%的食物，每月2-3次，持续10个月。暴露于过量Se的蛇在肾脏、肝脏和卵巢组织中积累了显著浓度的Se，但积累对雌性存活、食物消耗、生长或身体状况没有影响。暴露于过量硒的雌性比暴露于1杯/克硒的雌性生殖更少(分别为67%和91%)，但生殖活动的减少在统计学上并不显著。雌性生殖总产量在三种饲料处理之间没有差异。然而，暴露于10和20µg/g Se的蛇将大量的Se转移到它们的卵中。在20毫克/克的处理中，母体转移导致卵子中的硒浓度超过了所有建议的鸟类和鱼类生殖毒性阈值。需要进一步的研究来更严格地确定这种蛇物种的母体硒转移是否会影响发育中的胚胎的生存能力或后代的健康。由爱思唯尔公司出版。
Excessive concentrations of dietary Se are toxic to oviparous vertebrates (i.e., fish and birds) but little is known about its accumulation and effects in reptiles. We exposed female brown house snakes, Lamprophis fuliginosus, to 10 and 20 mug/g Se by injecting seleno-D,L-methionine into their prey items and compared the snakes to individuals receiving background levels of similar to1 mug/g dietary Se. Snakes were fed meals equaling 25% of their body mass 2-3 times a month for 10 months. Snakes exposed to excessive Se accumulated significant concentrations of Se in kidney, liver, and ovarian tissue, but accumulation had no effect on female survival, food consumption, growth, or body condition. Fewer females exposed to excessive Se reproduced than females exposed to 1 mug/g Se (67% vs. 91%, respectively), but the reduction in reproductive activity was not statistically significant. Total reproductive output of females did not differ among the three dietary treatments. However, snakes exposed to 10 and 20 mug/g Se transferred significant concentrations of Se to their eggs. In the 20 mug/g treatment, maternal transfer resulted in Se concentrations in eggs that surpassed all suggested reproductive toxicity thresholds for birds and fish. Further studies are needed to more rigorously determine whether maternal transfer of Se in this snake species affects the viability of developing embryos or the health of offspring. Published by Elsevier Inc.