EFFECT OF AGING ON THE ELECTROCARDIOGRAM
EFFECT OF AGING ON THE ELECTROCARDIOGRAM
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DOI：
10.1016/0002-9149(81)90081-3
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发表时间：
1981-01-01
影响因子：
2.8
通讯作者：
SMITH, LK
中科院分区：
文献类型：
--
作者：
BACHMAN, S;SPARROW, D;SMITH, LK
以前的横断面人群研究表明，年龄差异的心电图波模式，包括较低的波振幅和额面轴在老年人。然而，横截面的结果可能是由于队列差异和数据意味着这些变化实际上发生在人，因为他们的年龄。为了研究同一人群随年龄增长的心电图变化，我们对440名正常老化研究的健康男性参与者进行了连续记录，间隔10年，他们在第一次检查时年龄在23岁至66岁之间。在检查1，R和S波振幅较小，额面电轴测量移向左侧的老年男性。这些相同变量的纵向变化与横断面结果一致。第二次检查时P-R、Q-T间期延长，QRS时限缩短，T波振幅减小。S波振幅的纵向变化率在不同年龄组之间存在差异，年轻男性下降更多。因此，一些先前描述的横截面年龄差异真实地代表了心电图模式的纵向年龄趋势。
Previous cross-sectional population studies have shown age differences In electrocardiographic wave patterns, including lower wave amplitudes and a leftward shift of the frontal plane axis in older people. However, cross-sectional results may be due to cohort differences and the data imply only that these changes actually occur in persons as they age. In order to examine electrocardiographic changes with aging in the same persons, serial recordings, obtained 10 years apart, were taken in 440 healthy male participants of the Normative Aging Study, who were 23 to 66 years old on their first examination. At examination 1, R and S wave amplitudes were smaller and frontal plane axis measurements were shifted to the left in older men. Longitudinal changes in these same variables were consistent with the cross-sectional results. In addition, the P-R and Q-T interval durations were longer, the QRS duration was shorter and the T wave amplitude was smaller at the second examination. The longitudinal rate of change of S wave amplitude varied among age groups, decreasing more in younger men. Thus, some previously described cross-sectional age differences truly represent longitudinal age trends in electrocardiographic patterns.