IPSILATERAL CONNECTIONS OF THE ANTERIOR CINGULATE CORTEX WITH THE FRONTAL AND MEDIAL TEMPORAL CORTICES IN THE MACAQUE MONKEY
IPSILATERAL CONNECTIONS OF THE ANTERIOR CINGULATE CORTEX WITH THE FRONTAL AND MEDIAL TEMPORAL CORTICES IN THE MACAQUE MONKEY
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DOI：
10.1016/0168-0102(94)90065-5
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发表时间：
1994-11-01
影响因子：
2.9
通讯作者：
MURATA, A
中科院分区：
文献类型：
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作者：
ARIKUNI, T;SAKO, H;MURATA, A
用麦芽凝集素结合过氧化物酶(WGA-HRP)法研究猕猴同侧扣带回皮质前部(24区)的皮质联系。在4只日本猕猴(Macaca Fuscata)中，有2只将WGA-HRP注射到扣带回皮质前部，成功地将注射部位定位在24a和24b区对应的皮质区域。结果表明，扣带回皮质前部的24a和24b区与额叶前区、运动前区和运动皮质区以及内侧颞叶皮质区相互联系。24a区和24b区与前额叶外侧、内侧皮质和前运动皮质的6aβ区有较强的联系，与剩余的前运动皮质有中等的联系，与运动皮质的联系较弱。在内侧颞叶皮质，24a区和24b区与前小梁、内嗅皮质(28区)和咽周皮质(35区和36区)有较强的联系，而与海马旁回的Tf区和TH区有较弱的联系，贯穿它们的吻尾部。此外，24a区和24b区投射到Ammon‘s角的CA1亚区的分子层和小脑前部的外锥体层。我们的发现表明，前扣带回皮质的24a和24b区可能构成了前额叶皮质与海马区、内嗅区和/或周围皮质区之间相互通路的中继站。
The present study was attempted to study ipsilateral corticocortical connections of the anterior part (area 24) of the cingulate cortex of the macaque monkey by means of wheat germ agglutinin-conjugated peroxidase (WGA-HRP) method. in 2 out of 4 Japanese monkeys (Macaca fuscata) that were injected with WGA-HRP into the anterior part of the cingulate cortex, the sites of injection were successfully localized within the cortical regions corresponding to areas 24a and 24b. The results obtained from these monkeys indicate that areas 24a and 24b in the anterior part of the cingulate cortex are reciprocally connected with the prefrontal, premotor, and motor cortical regions, and also with the medial temporal cortical regions. Areas 24a and 24b were strongly connected with the lateral and medial prefrontal cortices and area 6a beta of the premotor cortex, moderately with the remaining premotor cortex, and weakly with the motor cortex. In the medial temporal cortex, areas 24a and 24b were strongly connected with the prosubiculum, entorhinal cortex (area 28), and perirhinal cortex (areas 35 and 36), and weakly with areas TF and TH of the parahippocampal gyrus, throughout their rostrocaudal extent. In addition, areas 24a and 24b projected to the molecular layer of the CAI subfield of Ammon's horn and the external pyramidal layer of the presubiculum. Our findings suggest that areas 24a and 24b of the anterior cingulate cortex may constitute relays in the reciprocal pathways between the prefrontal cortex and the hippocampal, entorhinal and/or perirhinal cortical regions.