ACQUIRED CYTOMEGALO-VIRUS INFECTION IN PRETERM INFANTS
ACQUIRED CYTOMEGALO-VIRUS INFECTION IN PRETERM INFANTS
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DOI：
10.1001/archpedi.1979.02130050026005
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发表时间：
1979-01-01
影响因子：
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通讯作者：
RIEDEL, PA
中科院分区：
文献类型：
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作者：
BALLARD, RA;DREW, WL;RIEDEL, PA
需要在新生儿重症监护病房护理超过 28 天的小病早产儿，在持续 13 个月的 2 个周期内，对尿液和/或鼻咽中的巨细胞病毒进行培养。 51 名此类婴儿中有 16 名在 28-148 天（平均 55 天）时开始排泄病毒。 16 例中，有 14 例出现了可识别的自限性综合症状，包括呼吸恶化、肝脾肿大、明显的灰色苍白以及非典型和绝对淋巴细胞增多。所有具有复杂临床症状的婴儿均患有潜在的慢性肺部疾病，并且在住院期间均接受了多次输血。获得性巨细胞病毒在患病早产儿中可能相对常见，应与迅速恶化的其他原因相鉴别。
Small sick preterm infants requiring care in a neonatal intensive care unit for more than 28 days were cultured for cytomegalovirus in urine and/or nasopharynx during 2 periods lasting a total of 13 mo. Sixteen of 51 such infants began excreting the virus at 28-148 days of age (mean, 55 days). In 14 of the 16, a recognizable, self-limited symptom complex developed that consisted of respiratory deterioration, hepatosplenomegaly, a remarkable gray pallor and both an atypical and absolute lymphocytosis. All of the infants with the clinical symptom complex had underlying chronic lung disease and all received multiple blood transfusion during their hospitalization. Acquired cytomegalovirus may be relatively common in sick preterm infants and should be distinguished from other causes of rapid deterioration.