Triterpenoid saponins from the roots of Clematis uncinata.

Triterpenoid saponins from the roots of Clematis uncinata.
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DOI:
10.1248/cpb.c13-00269
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发表时间:
2014
影响因子:
1.7
通讯作者:
Shuo-Guo Li;Xiao‐Jun Huang;Manmei Li;Mei Wang;Rui-Bing Feng;Wei Zhang;Yao-lan Li;Ying Wang
Shuo-Guo Li;Xiao‐Jun Huang;Manmei Li;Mei Wang;Rui-Bing Feng;Wei Zhang;Yao-lan Li;Ying Wang
中科院分区:
医学4区
文献类型:
--
作者:
Shuo-Guo Li;Xiao‐Jun Huang;Manmei Li;Mei Wang;Rui-Bing Feng;Wei Zhang;Yao-lan Li;Ying Wang

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Eight new bisdesmosidic triterpenoid saponins, clematiunicinosides A-H (1-8), along with eleven known ones (9-19), were isolated from the roots of Clematis uncinata. Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence. All the isolated saponins were tested for their cytotoxic activities on human caski cervical cancer (Caski) cells, and compounds 13, 17 and 19 exhibited inhibitory effect on Caski cells.