Octopamine-immunoreactive neurons in the brain and subesophageal ganglion of the hawkmoth Manduca sexta
Octopamine-immunoreactive neurons in the brain and subesophageal ganglion of the hawkmoth Manduca sexta
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DOI：
10.1002/cne.20556
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发表时间：
2005-08-01
影响因子：
2.5
通讯作者：
Hildebrand, JG
中科院分区：
文献类型：
--
作者：
Dacks, AM;Christensen, TA;Hildebrand, JG
章鱼胺是一种神经活性单胺，在许多无脊椎动物神经系统中充当神经激素、神经调节剂和神经递质，但人们对章鱼胺在大脑中的分布知之甚少。因此，我们使用单克隆抗体来研究天蛾 Manduca sexta 大脑中章鱼胺样免疫反应性的分布。在大脑的许多区域都观察到了免疫反应过程，但中央体的上部分除外。我们的分析重点是食管下神经节唇侧神经节中的九个腹侧受损中位（VUM）神经元，其细胞体。其中七个神经元通过腹神经索向尾部投射。两个神经元从嘴侧投射到大脑（食管上神经节），其中一个是双侧神经元，将投射发送到蘑菇体的伽玛叶和外侧原大脑。来自食管下神经节的一个或多个细胞的章鱼胺免疫反应过程也在触角叶和蘑菇体的肾盏之间形成直接连接。 (c) 2005 年 Wiley-Liss, Inc.
Octopamine is a neuroactive monoamine that functions as a neurohormone, a neuro-modulator, and a neurotransmitter in many invertebrate nervous systems, but little is known about the distribution of octopamine in the brain. We therefore used a monoclonal antibody to study the distribution of octopamine-like immunoreactivity in the brain of the hawkmoth Manduca sexta. Immunoreactive processes were observed in many regions of the brain, with the distinct exception of the upper division of the central body. We focused our analysis on nine ventral impaired median (VUM) neurons with cell bodies in the labial neuromere of the subesophageal ganglion. Seven of these neurons projected caudally through the ventral nerve cord. Two neurons projected rostrally into the brain (supraesophageal ganglion), and one of these was a bilateral neuron that sent projections to the gamma-lobe of the mushroom body and the lateral protocerebrum. Octopamine-immunoreactive processes from one or more cells originating in the subesophageal ganglion also form direct connections between the antennal lobes and the calyces of the mushroom bodies. (c) 2005 Wiley-Liss, Inc.