4D Flow MRI Applications for Aortic Disease
4D Flow MRI Applications for Aortic Disease
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DOI：
10.1016/j.mric.2014.08.006
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发表时间：
2015-02-01
影响因子：
1.6
通讯作者：
Hope, Michael D.
中科院分区：
文献类型：
--
作者：
Burris, Nicholas S.;Hope, Michael D.
主动脉疾病常规监测与解剖成像，但直到最近出现的3-方向相位对比MRI（4D）流，血流异常已被发现。4D Flow可快速测量主动脉血流动力学标志物。定性流动可视化刺激了新的定量标记物的研究。血流位移和壁面切应力可以量化瓣膜相关主动脉血流异常的影响。湍流和粘性能量损失的标记近似于疾病状态下心室上增加的能量负担。这篇文章讨论了磁共振血流成像，并强调了在主动脉瓣疾病、瓣膜相关主动脉疾病和主动脉壁疾病的背景下新的血流相关标志物。
Aortic disease is routinely monitored with anatomic imaging, but until the recent advent of 3-directional phase contrast MRI (4D) flow, blood flow abnormalities have gone undetected. 4D flow measures aortic hemodynamic markers quickly. Qualitative flow visualization has spurred the investigation of new quantitative markers. Flow displacement and wall shear stress can quantify the effects of valve-related aortic flow abnormalities. Markers of turbulent and viscous energy loss approximate the increased energetic burden on the ventricle in disease states. This article discusses magnetic resonance flow imaging and highlights new flow-related markers in the context of aortic valve disease, valve-related aortic disease, and aortic wall disease.