Neuroimaging in Tourette Syndrome: Research Highlights From 2014-2015.
Neuroimaging in Tourette Syndrome: Research Highlights From 2014-2015.
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DOI：
10.1007/s40474-015-0062-6
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发表时间：
2015-12
影响因子：
2
通讯作者：
Black KJ
中科院分区：
文献类型：
--
作者：
Greene DJ;Schlaggar BL;Black KJ
抽动秽语综合征（TS）是一种以慢性抽动为特征的中枢神经系统发育性神经精神障碍。虽然对潜在的脑机制的研究提供了有价值的信息，但对ts的病理生理学的完整理解仍然是难以捉摸的。神经影像学方法为检查人脑提供了显著的工具，并已被用于研究多发性硬化症患者的脑结构和功能。在这篇文章中，我们回顾了2014-2015年发表的神经影像学研究。我们强调了一些值得注意的研究，由于他们的创新方法和有趣的发现。然而，我们注意到，许多最近的研究有着共同的关注点，特别是对运动伪影的敏感性和适度的样本量。因此，我们鼓励未来的工作，认真解决潜在的方法学混淆，并研究更大的样本，以增加可复制的结果的潜力。
Tourette Syndrome (ts) is a developmental neuropsychiatric disorder of the central nervous system defined by the presence of chronic tics. While investigations of the underlying brain mechanisms have provided valuable information, a complete understanding of the pathophysiology of ts remains elusive. Neuroimaging methods provide remarkable tools for examining the human brain, and have been used to study brain structure and function in ts. In this article, we review ts neuroimaging studies published in 2014–2015. We highlight a number of noteworthy studies due to their innovative methods and interesting findings. Yet, we note that many of the recent studies share common concerns, specifically susceptibility to motion artifacts and modest sample sizes. Thus, we encourage future work to carefully address potential methodological confounds and to study larger samples to increase the potential for replicable results.