Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour.
Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour.
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心脏力学软件的验证：测试主动和被动物质行为的基准测试问题和解决方案。
DOI：
10.1098/rspa.2015.0641
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发表时间：
2015-12-08
期刊：
影响因子：
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通讯作者：
Niederer SA
中科院分区：
文献类型：
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作者：
Land S;Gurev V;Arens S;Augustin CM;Baron L;Blake R;Bradley C;Castro S;Crozier A;Favino M;Fastl TE;Fritz T;Gao H;Gizzi A;Griffith BE;Hurtado DE;Krause R;Luo X;Nash MP;Pezzuto S;Plank G;Rossi S;Ruprecht D;Seemann G;Smith NP;Sundnes J;Rice JJ;Trayanova N;Wang D;Jenny Wang Z;Niederer SA
心脏力学模型越来越多地用于研究心脏生理学。这些模型的特点是高度复杂，包括生物组织和主动收缩材料的特殊各向异性材料特性。目前已经开发了大量独立的仿真代码，但缺乏一种统一的方法来验证仿真的准确性和可复制性。为了帮助验证当前和未来的心脏力学解决方案，本研究为心脏力学提供了三个基准问题。这些基准问题测试了准确模拟压力型力的能力，这些力取决于变形物体的几何形状、各向异性和空间变化的材料特性，类似于左心室和主动收缩力。该基准由11个不同的组来求解，以产生一致的解，高分辨率解的典型差异约为0.5%，线性、二次和三次有限元以及模拟不可压缩材料的不同方法之间的结果一致。在线工具和解决方案可以使这些测试有效地用于验证未来的心脏力学软件。
Models of cardiac mechanics are increasingly used to investigate cardiac physiology. These models are characterized by a high level of complexity, including the particular anisotropic material properties of biological tissue and the actively contracting material. A large number of independent simulation codes have been developed, but a consistent way of verifying the accuracy and replicability of simulations is lacking. To aid in the verification of current and future cardiac mechanics solvers, this study provides three benchmark problems for cardiac mechanics. These benchmark problems test the ability to accurately simulate pressure-type forces that depend on the deformed objects geometry, anisotropic and spatially varying material properties similar to those seen in the left ventricle and active contractile forces. The benchmark was solved by 11 different groups to generate consensus solutions, with typical differences in higher-resolution solutions at approximately 0.5%, and consistent results between linear, quadratic and cubic finite elements as well as different approaches to simulating incompressible materials. Online tools and solutions are made available to allow these tests to be effectively used in verification of future cardiac mechanics software.