Diabetes and associated variables in the South Australian Aboriginal.
Diabetes and associated variables in the South Australian Aboriginal.
复制标题
南澳大利亚原住民的糖尿病和相关变量。
DOI：
10.1111/j.1445-5994.1976.tb03653.x
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发表时间：
1976
期刊：
影响因子：
--
通讯作者：
D. Thomas
中科院分区：
文献类型：
--
作者：
P. Wise;F. M. Edwards;R. J. Craig;B. Evans;J. B. Murchland;B. Sutherland;D. Thomas
一种主要的成熟型糖尿病在南澳大利亚原住民中的患病率被确认为高加索人的十倍。根据所提供的证据，营养状况和肥胖被认为是高血糖的主要病因，尽管全血土著人的相对高胰岛素血症表明存在显著的种族遗传效应。基于这些和其他理由，有人认为糖尿病基因可能代表了土著居民以前生存优势的一个因素，现在城市化使土著居民变得有害。高血糖的程度及其与高脂血症、肥胖、视网膜动静脉改变和异常心电图的关系，突出了糖尿病的重要性，并强调了在这些社区进行持续营养教育的迫切需要。
Diabetes of a predominant maturity-onset type has been identified as being up to ten times more prevalent in South Australian Aborigines than in Caucasians. On the evidence provided, nutritional status and obesity are thought to be dominant in the aetiology of the hyperglycaemia, although relative hyperinsulinaemia in full blood Aborigines suggests a significant racial genetic effect. It is suggested on these and other grounds that the diabetic genotype may represent a factor of previous survival advantage to the Aboriginal, now rendered deleterious by urbanization. The degree of hyperglycaemia, and its association with hyperlipidaemia, obesity, retinal arteriovenous changes and abnormal electrocardiographic findings, accentuates the significance of the diabetes, and underlines the serious need for ongoing nutritional education in these communities.