Immunotherapy and Hyperprogression: Unwanted Outcomes, Unclear Mechanism.
Immunotherapy and Hyperprogression: Unwanted Outcomes, Unclear Mechanism.
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DOI:
10.1158/1078-0432.ccr-18-3144
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发表时间:
2019-02-01
期刊:
影响因子:
--
通讯作者:
Ravetch JV
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文献类型:
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作者:
Knorr DA;Ravetch JV
Hyperprogression (HP) is a recently defined clinical phenomenon in which patients treated with immunotherapy paradoxically exhibit rapid tumor growth. The mechanisms of HP remain ill-defined though recent studies in this issue point to a possible role for Fc receptors in this process.