Specific and nonspecific Comorbidity in anorexia nervosa
Specific and nonspecific Comorbidity in anorexia nervosa
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DOI：
10.1002/eat.20463
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发表时间：
2008-01-01
影响因子：
5.5
通讯作者：
Bulik, Cynthia M.
中科院分区：
文献类型：
--
作者：
Jordan, Jennifer;Joyce, Peter R.;Bulik, Cynthia M.
目的：本文报道神经性厌食症（AN）女性一生I轴和II轴的共病，并确定AN与神经性贪食症（BN）或重度抑郁症（DEP）女性临床样本的特异性和非特异性共病。方法：门诊AN （n = 56）、BN （n = 132）和DEP （n = 100）样本采用DSM-III-R的结构化临床访谈I和II进行评估。基线数据采用单变量统计和逻辑回归进行比较。结果：在整个AN样本中，发现强迫症的患病率有特定的升高。an -暴食清除亚型（AN-BP）和BN样本的B类人格障碍患病率升高。C类患病率在整个样本中都有所升高。结论：AN特异性、饮食失调特异性和非特异性合并症的证据说明了AN的异质性。需要进一步研究特异性和非特异性合并症对AN亚型和AN整体的相对影响。(C) 2007年由Wiley期刊公司出版。
Objective: This article reports lifetime Axis I and II comorbidity in women with anorexia nervosa (AN), and ascertains specific and nonspecific comorbidity in AN compared to clinical samples of women with bulimia nervosa (BN) or major depression (DEP).Method: Outpatient AN (n = 56), BN (n = 132), and DEP (n = 100) samples were assessed using Structured Clinical interviews I and II for DSM-III-R. Baseline data were compared using univariate statistics and logistic regression.Results: In the AN sample as a whole, specific elevations were found for prevalences of obsessive compulsive disorder. The AN-binge eating purging subtype (AN-BP) and the BN sample had elevated prevalences of Cluster B personality disorders. Cluster C prevalences were elevated across samples.Conclusion: Evidence of AN-specific, eating disorder-specific, and nonspecific comorbidity illustrates the heterogeneity in AN. Further research is need to examine the relative impact of specific and nonspecific comorbidity in AN subtypes and AN as a whole. (C) 2007 by Wiley Periodicals, Inc.