Left ventricular hypertrophy and ventricular dysrhythmic risk in hypertensive patients: evaluation by programmed electrical stimulation
Left ventricular hypertrophy and ventricular dysrhythmic risk in hypertensive patients: evaluation by programmed electrical stimulation
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高血压患者的左心室肥厚和心室节律失常风险：通过程序化电刺激进行评估
DOI：
10.1097/00004872-198812040-00033
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发表时间：
1988
影响因子：
4.9
通讯作者：
H. Bricaud
中科院分区：
文献类型：
--
作者：
P. Coste;J. Clémenty;P. Besse;H. Bricaud
高血压患者左心室肥厚与室性心律失常的发生率增加有关。对12例经M型超声心动图评估为左心室肥厚的患者和12例无左心室肥厚的患者进行了程序电刺激的电生理研究。左室肥厚患者结下传导时间延长，且与左室质量密切相关（r = 0.71; P < 0.001）。与对照组相比，程序电刺激在左心室肥厚组中引发更多的心室内折返和非持续性室性心动过速，尽管从未诱导持续性室性心动过速。我们的结论是，高血压患者左心室肥厚，特别是在那些心电图证据的左心室肥厚的心室脆弱性增加。
Left ventricular hypertrophy in hypertensive patients is associated with an increased prevalence of ventricular arrhythmias. Twelve patients with left ventricular hypertrophy assessed by M-mode echocardiography and 12 without left ventricular hypertrophy underwent an electrophysiological study with programmed electrical stimulation. The patients with left ventricular hypertrophy had a prolonged infranodal conduction time which correlated closely with left ventricular mass (r = 0.71; P < 0.001). Programmed electrical stimulation initiated more intraventricular re-entry and unsustained ventricular tachycardia in the group with left ventricular hypertrophy than in the control group, although sustained ventricular tachycardia was never induced. We conclude that ventricular vulnerability is increased in hypertensive patients with left ventricular hypertrophy, especially in those who show electrocardiographic evidence of left ventricular hypertrophy.