Subclinical hyperthyroidism as a risk factor for atrial fibrillation

Subclinical hyperthyroidism as a risk factor for atrial fibrillation
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DOI:
10.1067/mhj.2001.119370
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发表时间:
2001-11-01
影响因子:
4.8
通讯作者:
Eber, B
Eber, B
中科院分区:
医学2区
文献类型:
--
作者:
Auer, J;Scheibner, P;Eber, B

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目的心房颤动是甲状腺功能亢进症的常见表现。我们研究是否亚临床甲状腺功能亢进症低血清促甲状腺激素浓度和游离甲状腺激素浓度在正常范围内的临床甲状腺功能正常的人是一个危险因素,随后的房颤。受试者根据血清促甲状腺激素浓度分类:第1组为血清促甲状腺激素浓度正常者(>0.4-5.0 mU/L),游离三碘甲状腺原氨酸和游离甲状腺素浓度在正常范围内(22,300例受试者),第2组为血清促甲状腺激素水平低的患者,(小于或等于0.03 mU/L)和游离三碘甲状腺原氨酸和游离甲状腺素浓度升高(725例受试者),第3组包括血清促甲状腺激素值低(
Objectives Atrial fibrillation is a well-known manifestation of hyperthyroidism. We studied whether subclinical hyperthyroidism with low serum thyrotropin concentrations and free thyroid hormone concentrations within the normal range in clinically euthyroid persons is a risk factor for subsequent atrial fibrillation.Methods We studied 23,638 persons. The subjects were classified according to their serum thyrotropin concentrations: group 1 comprised those with normal values of serum thyrotropin concentration (>0.4-5.0 mU/L) and free tri-iodothyronine and free thyroxine concentrations were within the normal range (22,300 subjects), group 2 comprised those with both low serum thyrotropin values (less than or equal to0.03 mU/L) and elevated free tri-iodothyronine and free thyroxine concentrations (725 subjects), and group 3 comprised those with low values of serum thyrotropin (