A high-performance protein crystallization plate pre-embedded with crosslinked protein microcrystals as seeds

A high-performance protein crystallization plate pre-embedded with crosslinked protein microcrystals as seeds
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DOI:
10.1039/c8ce00807h
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发表时间:
2018-08
期刊:
影响因子:
3.1
通讯作者:
H. Hou;Miao Shi;Zhong-hao Chen;Fiaz Ahmad;Yue Liu;Er-Kai Yan;Chao Luo;Jing Li;Chengtian Zhu-Cheng
H. Hou;Miao Shi;Zhong-hao Chen;Fiaz Ahmad;Yue Liu;Er-Kai Yan;Chao Luo;Jing Li;Chengtian Zhu-Cheng
中科院分区:
化学3区
文献类型:
--
作者:
H. Hou;Miao Shi;Zhong-hao Chen;Fiaz Ahmad;Yue Liu;Er-Kai Yan;Chao Luo;Jing Li;Chengtian Zhu-Cheng

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新型板的威尔斯孔预先包埋有交联的蛋白质微晶,其可以充当蛋白质结晶的种子。结晶筛选实验结果表明,与原有的CDM板相比,新型板在寻找结晶条件方面表现出显着改善的性能。
The wells of the novel plate are pre-embedded with cross-linked protein microcrystals which can act as the seeds for protein crystallization. The results of crystallization screening experiments showed that the novel plate exhibited dramatically improved performance in finding crystallization conditions as compared with the original CDM plate.