Elimination of False-Positive Results in a Luminex Assay for Pneumococcal Antibodies
Elimination of False-Positive Results in a Luminex Assay for Pneumococcal Antibodies
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DOI：
10.1128/cvi.00329-09
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发表时间：
2010-01-01
影响因子：
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通讯作者：
Hill, Harry R.
中科院分区：
文献类型：
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作者：
Pickering, Jerry W.;Larson, Matthew T.;Hill, Harry R.
在我们的14价Luminex肺炎球菌抗体测定中，我们确定了两组导致假阳性结果的血清。第一组与Luminex微球非特异性结合。第二组与牛血清白蛋白（BSA）特异性反应。我们在这里描述了消除两组假阳性反应的方法。
In our 14-valent Luminex assay for pneumococcal antibodies, we identified two groups of sera that caused false-positive results. The first group bound nonspecifically to the Luminex microspheres. The second group reacted specifically with bovine serum albumin (BSA). We describe here methods that eliminated the false-positive reactivity of both groups.