LANGERHANS CELLS IN HUMAN-LUNG TUMORS - AN IMMUNOHISTOLOGICAL STUDY
LANGERHANS CELLS IN HUMAN-LUNG TUMORS - AN IMMUNOHISTOLOGICAL STUDY
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DOI：
10.1111/j.1365-2559.1989.tb02145.x
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发表时间：
1989-03-01
期刊：
影响因子：
6.4
通讯作者：
MASON, DY
中科院分区：
文献类型：
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作者：
FOX, SB;JONES, M;MASON, DY
在对41例人肺肿瘤的免疫细胞化学研究中，我们发现使用抗CD 1单克隆抗体NA 1/34可以可靠地鉴定朗格汉斯细胞。朗格汉斯细胞存在于所有主要的人类肺肿瘤中，尽管它们在小细胞癌和类癌肿瘤中都很少见。在腺癌和鳞状细胞癌中郎格罕细胞的数量有相当大的变化。在这项研究中，将肿瘤分为朗格汉斯细胞数量高的肿瘤（每个高倍视野>2个）和数量低的肿瘤（
In an immunocytochemical study of 41 human lung tumours we have shown that Langerhans cells can be reliably identified using the anti-CD1 monoclonal antibody NA1/34. Langerhans cells are present in all the main varieties of human lung tumour although they are infrequent in both small cell carcinoma and carcinoid tumour. There is considerable variation in numbers of Langerhans cells in both adenocarcinomas and squamous cell carcinomas. In this study tumours were divided into those with high numbers of Langerhans cells (>2 per high power field) and those with low numbers (