Somatic markers and response reversal: Is there orbitofrontal cortex dysfunction in boys with psychopathic tendencies?
Somatic markers and response reversal: Is there orbitofrontal cortex dysfunction in boys with psychopathic tendencies?
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DOI：
10.1023/a:1012277125119
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发表时间：
2001-12-01
影响因子：
3.6
通讯作者：
Mitchell, DGV
中科院分区：
文献类型：
--
作者：
Blair, RJR;Colledge, E;Mitchell, DGV
这项研究调查了9至17岁的有精神病倾向的男孩和对照男孩在两项任务上的表现，这两项任务被认为对杏仁核和眶额皮质功能敏感。51名男孩根据精神病筛查设备（PSD，P. J.弗里克& R。D. Hare，in press），并提出了两项任务。这些任务是赌博任务（A。Bechara，A. R.达马西奥H. Damasio，& S. W.安德森，1994）和维度内/维度外（ID/艾德）转换任务（R. Dias，T. W. Robbins，& A. C. Roberts，1996）。有精神病倾向的男孩在赌博任务中表现不佳。然而，在ID/艾德任务上，无论是反应逆转还是额外维度的集合转移，都没有组间差异。这些结果的精神病模型的影响进行了讨论。
This study investigated the performance of boys with psychopathic tendencies and comparison boys, aged 9 to 17 years, on two tasks believed to be sensitive to amygdala and orbitofrontal cortex functioning. Fifty-one boys were divided into two groups according to the Psychopathy Screening Device (PSD, P. J. Frick & R. D. Hare, in press) and presented with two tasks. The tasks were the gambling task (A. Bechara, A. R. Damasio. H. Damasio, & S. W. Anderson, 1994) and the Intradimensional/Extradimensional (ID/ED) shift task (R. Dias, T. W. Robbins, & A. C. Roberts, 1996). The boys with psychopathic tendencies showed impaired performance on the gambling task. However, there were no group differences on the ID/ED task either for response reversal or extradimensional set shifting. The implications of these results for models of psychopathy are discussed.