Increasing incidence of resistance to nalidixic acid in shigellas from humans in England and Wales: implications for therapy

Increasing incidence of resistance to nalidixic acid in shigellas from humans in England and Wales: implications for therapy
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DOI:
10.1111/j.1469-0691.2004.00982.x
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发表时间:
2004-11-01
影响因子:
14.2
通讯作者:
Threlfall, EJ
Threlfall, EJ
中科院分区:
医学1区
文献类型:
--
作者:
Cheasty, T;Day, M;Threlfall, EJ

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Among shigellas isolated from patients in England and Wales in 2002, 10% of subgroups A, B and C, and 13% of subgroup D (Shigella sonnei), were resistant to nalidixic acid. As a consequence, should antimicrobial therapy be indicated, the efficacy of nalidixic acid as the preferred treatment for children with bacillary dysentery has been jeopardised.