THE REACTION OF CYANOGEN WITH ORGANIC COMPOUNDS. V. MERCAPTANS1,2
THE REACTION OF CYANOGEN WITH ORGANIC COMPOUNDS. V. MERCAPTANS1,2
复制标题
氰与有机化合物的反应。
DOI：
10.1021/jo01137a007
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发表时间：
1952
影响因子：
3.6
通讯作者：
C. E. Sroog
中科院分区：
文献类型：
--
作者：
H. Woodburn;C. E. Sroog
372..伍德伯恩和C.E.SROOG研究有机物与氰化物的反应(6)研究不同酸度的硫醇是很有意义的。因此，不仅研究了一系列脂肪族硫醇，还研究了硫酚、某些对取代的硫酚(氯、甲基和硝基)和硫代硫酚。硫酚比脂肪族硫醇(7)酸性更强，这种类型的对位取代将改变氢的活性，而不会引入可能导致O/O/O取代的复杂影响。所有被研究的化合物，包括硫酚，在碱性催化剂存在的情况下，都很容易与氰基反应。在没有催化剂的情况下，没有反应发生。使用纯液体硫醇或固体在无水溶剂中的溶液，在反应过程中将温度保持在接近0。
372.. WOODBURN AND C. E. SROOG erty of organic substances reacting with cyanogen (6) it was of interest to work with mercaptans of varying acidity. Accordingly, not only a series of aliphatic mercaptans, but also thiophenol, certain para-substituted thiophenols (chloro, methyl, and nitro), and thiophenethiol were investigated. Thiophenol is more acidic than an aliphatic mercaptan (7) and para-substitution of the kind in-dicated would vary the hydrogen activity withoutintroducing the complicating effects that might result from ort/io-substitution. All the compounds investigated, including thiophenol, reacted easily with cyanogen providing there was present a basic catalyst. No reaction occurred in the absence of the catalyst. The pure liquid mercaptan or a solution of the solid in an anhydrous solvent was used, the temperature being maintained close to 0 during the reaction.