Controlling molecular diffusion in self-spreading lipid bilayer using periodic array of ultra-small metallic architecture on solid surface
Controlling molecular diffusion in self-spreading lipid bilayer using periodic array of ultra-small metallic architecture on solid surface
复制标题
DOI：
10.1021/ja0559597
复制
发表时间：
2005-12-07
影响因子：
15
通讯作者：
Murakoshi, K
中科院分区：
文献类型：
--
作者：
Nabika, H;Sasaki, A;Murakoshi, K
通过在固体表面引入金属结构的周期性阵列来控制目标分子在自展开脂质双层中的扩散。当小金属结构之间的间隙尺寸小于几百纳米时，目标分子的进展的延迟变得显著。半定量地分析了脂双层的自扩散动力学随小间隙大小的变化。在扩展层的驱动力的估计的变化表明，高度局部化的压缩的扩展层的原因选择性分离的分子。
Diffusion of target molecules incorporated in the self-spreading lipid bilayer was controlled by the introduction of periodic array of metallic architecture on solid surface. Retardation of the progress of target molecules became significant when the size of gap between small metal architectures was less than a few hundred nanometers. The self-spreading dynamics of the lipid bilayer depending on the size of the small gap were analyzed semiquantitatively. Estimated change in the driving force of the spreading layer suggests that highly localized compression of the spreading layer causes selective segregation of molecules.