Direct W-like geniculate projections to the cytochrome oxidase (CO) blobs in primate visual cortex: axon morphology.
Direct W-like geniculate projections to the cytochrome oxidase (CO) blobs in primate visual cortex: axon morphology.
复制标题
灵长类视觉皮层中细胞色素氧化酶（CO）斑点的直接W状膝状投影：轴突形态。
DOI：
10.1002/cne.903190112
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
Casagrande,VA
中科院分区：
文献类型：
--
作者：
Lachica,EA;Casagrande,VA
灵长类动物外侧膝状核（LGN）由大细胞、中细胞和小细胞组成，分别位于大细胞层(M)、小细胞层(P)和特化层（类人猿的插层和S层，原猿的孔细胞层(K)）。一些研究已经检查了M和P LGN细胞的生理和连接，并得出结论，它们通过不同的途径对视觉感知提供不同的贡献。对小LGN细胞的结构和作用了解较少。本研究研究了原猴皮层K - LGN细胞轴突的分布和结构。将与辣根过氧化物酶结合的小麦胚芽凝集素（phaseonlus vulgarisleucoagglutinin）注射到LGN K层中，分别显示轴突的整体投影模式和单个轴突的细节。纹状皮层内轴突的位置相对于同一或相邻切片上的尼氏染色或细胞色素氧化酶（CO）染色确定的边界来指定。我们的研究结果表明，K - LGN轴突在第三层的一个CO blob区域内以单个复杂的轴突结束；它们从不终止于斑点间区。这些轴突也在第一层释放侧枝，其范围更广，跨越CO斑点区和斑点间区。这些数据，连同K细胞生理学和层间皮质连接的数据，表明LGN小细胞通路可以调节纹状皮层中其他两条通路的活性，并直接参与视觉感知。©1992 Wiley‐Liss, Inc。
The primate lateral geniculate nucleus (LGN) is composed of large, medium, and small cells located, respectively, in magnocellular (M), parvocellular (P), and specialized layers (intercalated and S‐layers in simians, koniocellular (K) layers in prosimians). Several studies have examined the physiology and connections of M and P LGN cells and have concluded that they provide separate contributions to visual perception via separate pathways. Less is known about the structure and contributions of the small LGN cells. This study examined the distribution and structure of K LGN cell axons in the cortex of the prosimian,Galago crassicaudatus. Wheat germ agglutinin conjugated to horseradish peroxidase, orPhaseonlus vulgarisleucoagglutinin, was injected into the LGN K layers to demonstrate the overall axon projection pattern and the details of individual axons, respectively. Location of axons within striate cortex was specified relative to boundaries determined by Nissl or cytochrome oxidase (CO) stains on the same or adjacent sections.Our results show that K LGN axons end as single complex arbors within one CO blob zone in layer III; they never terminate in interblob zones. These axons also emit a collateral in layer I that arborizes more broadly and spans both CO blob and interblob zones. These data, together with data on K cell physiology and intralaminar cortical connections, suggest that the LGN small cell pathway could modulate the activity of the other two pathways in striate cortex and contribute directly to visual perception. © 1992 Wiley‐Liss, Inc.