Vasovagal syncope after infusion of a vasodilator in a heart-transplant recipient.
Vasovagal syncope after infusion of a vasodilator in a heart-transplant recipient.
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心脏移植受者输注血管扩张剂后出现血管迷走性晕厥。
DOI：
10.1056/nejm199003013220906
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Victor,RG
中科院分区：
文献类型：
--
作者：
Scherrer,U;Vissing,S;Morgan,BJ;Hanson,P;Victor,RG
众所周知，低血压状态会激活交感神经系统，导致反射性血管收缩和心动过速。1然而，低血容量性低血压可能伴随交感神经冲动的矛盾撤回，导致血管扩张和心动过缓--这反过来又加剧血压下降的反应。2345在人类中，在失血性休克期间观察到低血压，心率不适当地正常或明显减慢，6在注射血管扩张剂6之后，7最近，在直立倾斜试验中注射异丙肾上腺素，这是用来引起晕厥的。8，9目前认为这种类型的血管降压反应是一种。
HYPOTENSIVE states are well known to activate the sympathetic nervous system, leading to reflex vasoconstriction and tachycardia.1Hypovolemic hypotension, however, can be accompanied by paradoxical withdrawal of sympathetic drive, leading to vasodilation and bradycardia — responses that, in turn, exacerbate the decrease in blood pressure.2345In humans, hypotension with an inappropriately normal or frankly decreased heart rate has been observed during hemorrhagic shock,6after the infusion of vasodilators,7and most recently, in response to the infusion of isoproterenol during the upright-tilt test, which is used to provoke syncope.8,9The current belief is that this type of vasodepressor reaction is a . . .