Effects of exercise before breakfast on plasma free fatty acid profile and 24-h fat oxidation.
Effects of exercise before breakfast on plasma free fatty acid profile and 24-h fat oxidation.
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DOI：
10.1016/j.metop.2020.100067
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发表时间：
2020-12
期刊：
影响因子：
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通讯作者：
Tokuyama K
中科院分区：
文献类型：
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作者：
Iwayam K;Ogawa A;Tanaka Y;Yajima K;Park I;Ando A;Ogata H;Kayaba M;Zhang S;Tanji F;Nabekura Y;Yamamoto K;Tokuyama K
游离脂肪酸(FFA)是一种重要的能量来源，也是调节基因表达的信号分子。在摄取后状态下进行的运动，与在餐后状态下进行的运动相比，在能量平衡的条件下增加了24小时的脂肪氧化。本研究的主要目的是阐明运动对血浆游离脂肪酸浓度和组成的影响是否取决于运动时个体的营养状态，这可能是运动对24小时脂肪氧化的不同影响的基础。10名健康的年轻男子在代谢室进行了3次间接量热法试验。受试者在摄取后或餐后状态下，以60%的最大摄氧量进行60min的锻炼，或者保持久坐不锻炼(对照组)。所有试验都被设计为在24小时内保持能量平衡。运动前和运动后立即采集血样。只有在吸收后状态下进行运动时，24小时以上的脂肪氧化才会增加(对照组，531千卡±0.60千卡；吸收后，779千卡±0.70千卡；餐后，569千卡±0.37千卡/24小时)。24小时脂肪氧化增加与运动后一过性碳水化合物缺乏的程度有关。运动后血浆游离脂肪酸浓度(0.38±0.04)高于对照组(0.13±0.01)和餐后(0.15±0.02)mm。运动后试验不饱和/饱和(U/S)比值(1.76±0.06)高于对照组(1.56±0.07)和餐后试验(1.53±0.08)。另一方面，餐后状态下运动后的血浆FFA浓度与对照试验没有显著差异。与餐后运动相比，吸收后运动能更有效地提高血浆游离脂肪酸浓度和U/S比值，从而导致24小时脂肪氧化增加。血浆游离脂肪酸浓度的升高与运动后短暂的碳水化合物缺乏有关。在吸收后状态下进行的运动会增加24小时的脂肪氧化。在吸收后状态进行运动可增加U/S比值。血浆游离脂肪酸浓度与一过性碳水化合物缺乏有关。
Free fatty acids (FFAs) are an important source of energy, and also serve as signaling molecules to regulate gene expression. Exercise performed in a post-absorptive state, in contrast to that performed in a postprandial state, increases 24-h fat oxidation under an energy-balanced condition. The primary aim of the present study was to clarify whether the effects of exercise on the concentration and composition of plasma FFAs, which may underlie distinct effects of exercise on 24-h fat oxidation, depend on the nutritional state of the individual when performing the exercise. Ten healthy young men underwent 3 trials of indirect calorimetry in a metabolic chamber. The subjects performed exercise at 60% of VO2max for 60 min in either a post-absorptive or postprandial state, or remained sedentary without an exercise session (control). All trials were designed to be energy balanced over 24 h. Blood samples were collected immediately before and after exercise. Fat oxidation over 24 h was increased only when exercise was performed in a post-absorptive state (control, 531 ± 60; post-absorptive, 779 ± 70; postprandial, 569 ± 37 kcal/24 h). The increase in the 24-h fat oxidation was related to the magnitude of the transient carbohydrate deficit after exercise. The plasma FFA concentration after exercise was higher in the post-absorptive trial (0.38 ± 0.04) than in the control (0.13 ± 0.01) and postprandial (0.15 ± 0.02 mM) trials. The ratio of unsaturated to saturated (U/S) fatty acids after exercise was higher in the post-absorptive trial (1.76 ± 0.06) than in the control (1.56 ± 0.07) and postprandial (1.53 ± 0.08) trials. On the other hand, the plasma FFA concentration after exercise in a postprandial state did not differ significantly from that in the control trial. Exercise performed in a post-absorptive state effectively increased the plasma FFA concentration and U/S ratio to a greater degree than exercise performed in a postprandial state, underlying the increase in the 24-h fat oxidation. The increase in the plasma FFA concentration was related to the transient carbohydrate deficit after exercise. Exercise performed in post-absorptive state increases 24-h fat oxidation. Exercise performed in a post-absorptive state increased the ratio of U/S ratio. The plasma FFA concentration was related to the transient carbohydrate deficit.