Retinal Fractals and Acute Lacunar Stroke
Retinal Fractals and Acute Lacunar Stroke
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DOI：
10.1002/ana.22011
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发表时间：
2010-07-01
影响因子：
11.2
通讯作者：
Wong, Tien Y.
中科院分区：
文献类型：
--
作者：
Cheung, Ning;Liew, Gerald;Wong, Tien Y.
本研究旨在确定视网膜分形维数（微血管分支复杂性和密度的定量测量）是否与腔隙性卒中相关。共有392例急性缺血性卒中患者通过数字照片测量视网膜分形维数，并通过脑成像确定腔隙性梗死。在调整年龄、性别和血管危险因素后，较高的视网膜分形维数（最高与最低四分位数和每标准差增加）与腔隙性卒中独立正相关（比值比[OR]，4.27; 95%置信区间[CI]，1.49-12.17和OR，1.85; 95%CI，1.20-2.84）。视网膜微血管复杂性和密度增加与腔隙性卒中相关神经网络2010;68：107-111
This study aimed to determine whether retinal fractal dimension, a quantitative measure of microvascular branching complexity and density, is associated with lacunar stroke. A total of 392 patients presenting with acute ischemic stroke had retinal fractal dimension measured from digital photographs, and lacunar infarct ascertained from brain imaging. After adjusting for age, gender, and vascular risk factors, higher retinal fractal dimension (highest vs lowest quartile and per standard deviation increase) was independently and positively associated with lacunar stroke (odds ratio [OR], 4.27; 95% confidence interval [CI], 1.49-12.17 and OR, 1.85; 95% CI, 1.20-2.84, respectively). Increased retinal microvascular complexity and density is associated with lacunar stroke. ANN NEUROL 2010;68:107-111