Retinal discoloration test
Retinal discoloration test
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DOI：
10.1097/01.wcb.0000107731.66603.18
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发表时间：
2004-03-01
影响因子：
6.3
通讯作者：
Hartl, T
中科院分区：
文献类型：
--
作者：
Joshi, S;Wang, M;Hartl, T
新西兰白兔颈内动脉 (ICA) 的大小和起源存在很大差异。一项能够正确识别 ICA 的简单测试可以促进药物和栓塞材料的颈动脉内输送，以便在这些动物身上进行研究。事实证明，五种用于识别 ICA 的传统方法不如新型视网膜变色测试 (RDT)。 RDT 阳性意味着注射 0.2 mL 靛胭脂蓝 (ICB) 后视网膜反射颜色发生变化。我们得出的结论是，RDT 是正确识别和分离该动物物种中 ICA 的有用测试。
There are considerable variations in the size and the origin of internal carotid arteries (ICAs) of New Zealand white rabbits. A simple test that could correctly identify the ICA could facilitate intracarotid delivery of drugs and embolic material for research in these animals. Five conventional methods for identifying the ICA proved inferior to a novel retinal discoloration test (RDT). A positive RDT implies a change in color of the retinal reflex after injection of 0.2 mL of indigocarmine blue (ICB). We conclude that RDT is a useful test for correctly identifying and isolating the ICA in this animal species.