Catenanes: fifty years of molecular links.
Catenanes: fifty years of molecular links.
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DOI：
10.1002/anie.201411619
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发表时间：
2015-05-18
期刊：
影响因子：
--
通讯作者：
Stephens AJ
中科院分区：
文献类型：
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作者：
Gil-Ramírez G;Leigh DA;Stephens AJ
在Schill和l<s:2> ttringhaus首次定向合成[2]链烷半个世纪后，现在存在大量的策略来构建分子Hopf链（单链环），这是最简单的链烷类型。合适的模板和/或非共价相互作用可以精确而有效地排列构建块，也使得合成复杂且通常是美丽的高阶联锁系统成为可能，包括所罗门链、博罗米安环和大卫之星链烷。本文概述了21世纪存在的多种链烷合成策略，并研究了它们的新兴应用以及合成更复杂拓扑结构仍然存在的挑战。
Half a century after Schill and Lüttringhaus carried out the first directed synthesis of a [2]catenane, a plethora of strategies now exist for the construction of molecular Hopf links (singly interlocked rings), the simplest type of catenane. The precision and effectiveness with which suitable templates and/or noncovalent interactions can arrange building blocks has also enabled the synthesis of intricate and often beautiful higher order interlocked systems, including Solomon links, Borromean rings, and a Star of David catenane. This Review outlines the diverse strategies that exist for synthesizing catenanes in the 21st century and examines their emerging applications and the challenges that still exist for the synthesis of more complex topologies.