Closely Related Fruit Fly Species Living at Different Latitudes Diverge in Their Circadian Clock Anatomy and Rhythmic Behavior
Closely Related Fruit Fly Species Living at Different Latitudes Diverge in Their Circadian Clock Anatomy and Rhythmic Behavior
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DOI：
10.1177/0748730418798096
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发表时间：
2018-12-01
影响因子：
3.5
通讯作者：
Helfrich-Foerster, Charlotte
中科院分区：
文献类型：
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作者：
Beauchamp, Marta;Bertolini, Enrico;Helfrich-Foerster, Charlotte
最近，我们报道了蓝光敏感的黄素蛋白隐花色素（CRY）和神经肽色素分散因子（PDF）的表达模式的差异，在高纬度的果蝇种，属于果蝇亚属（virilis-repleta辐射），与cosmopolitan D.黑腹果蝇，属于Sophophora亚属。由于这些差异，在节奏的活动模式的变化可能具有适应意义的殖民高纬度的栖息地，因此，适应长的光周期。在这里，我们表明，这些不同的CRY/PDF表达模式只存在于这些物种的virilis-repleta辐射，殖民高纬度地区。广布种D. mercatorum和D. hydei有一个D。黑色素样的时钟网络和行为，尽管属于男性化-repleta辐射。同样，全热带的Zaprionus属的两个种，与果蝇亚属的关系比与Sophophora亚属的关系更密切，保留了D。黑胃样生物钟网络和节律行为。因此，我们建议D.黑素胃样生物钟网络是“祖先苍蝇生物钟表型”，CRY/PDF生物钟神经化学的改变使某些种的雄性生殖细胞-生殖细胞辐射能够在高纬度环境中定居。
Recently, we reported differences in the expression pattern of the blue light-sensitive flavoprotein cryptochrome (CRY) and the neuropeptide pigment-dispersing factor (PDF) in the neuronal clock network of high-latitude Drosophila species, belonging to the Drosophila subgenus (virilis-repleta radiation), compared with cosmopolitan D. melanogaster flies, belonging to the Sophophora subgenus. Alterations in rhythmic patterns of activity due to these differences might have adaptive significance for colonizing high-latitude habitats and, hence, adjusting to long photoperiods. Here, we show that these differing CRY/PDF expression patterns are only present in those species of the virilis-repleta radiation that colonized high latitudes. The cosmopolitan species D. mercatorum and D. hydei have a D. melanogaster-like clock network and behavior despite belonging to the virilis-repleta radiation. Similarly, 2 species of the holotropical Zaprionus genus, more closely related to the Drosophila subgenus than to the Sophophora subgenus, retain a D. melanogaster-like clock network and rhythmic behavior. We therefore suggest that the D. melanogaster-like clock network is the "ancestral fly clock phenotype" and that alterations in the CRY/PDF clock neurochemistry have allowed some species of the virilis-repleta radiation to colonize high-latitude environments.