Percutaenous mitral valve: A non-stented coronary sinus device for the treatment of functional mitral regurgitation in heart failure patients
Percutaenous mitral valve: A non-stented coronary sinus device for the treatment of functional mitral regurgitation in heart failure patients
复制标题
经皮二尖瓣：一种用于治疗心力衰竭患者功能性二尖瓣反流的无支架冠状窦装置
DOI：
10.1080/13645700902951044
复制
发表时间：
2009
影响因子：
1.7
通讯作者：
R. Erbel
中科院分区：
文献类型：
--
作者：
S. Sack;P. Kahlert;R. Erbel
心力衰竭中的功能性二尖瓣返流以严重程度分级的方式限制生存。即使是轻微的二尖瓣返流，死亡风险也会加倍。我们报告使用无支架冠状静脉窦装置来缩小二尖瓣环的内径，以重建二尖瓣功能。该设备(位于美国马萨诸塞州威尔明顿的维亚科™公司)由多腔聚四氟乙烯(特氟龙)聚四氟乙烯导管组成，其中先进了镍钛合金治疗棒。对于个人使用，最多可以使用三根不同长度和刚度的杆。因此，可以以增量的方式执行降维。在整个手术过程中都进行了透视和三维超声心动图检查，以观察定位并确认最大的治疗效果。该病例描述了PTMA治疗的使用和效果。PTMA装置的安全性和有效性将在即将到来的托勒密2号试验中进行调查。
Functional mitral regurgitation in heart failure limits survival in a severity-graded fashion. Even mild mitral regurgitation doubles mortality risk. We report the use of a non-stented coronary sinus device to reduce mitral annulus dimension in order to re-establish mitral valve competence. The device (PTMA™, Viacor, Inc., Wilmington, MA, USA) consists of a multi-lumen PTFE (Teflon) PTMA catheter in which Nitinol (nickel-titanium alloy) treatment rods are advanced. For individual use up to three rods of different length and stiffness can be used. Therefore dimension reduction can be performed in an incremental fashion. Fluoroscopy and 3 D echocardiography are performed throughout the procedure to visiualize the positioning and confirm maximum treatment effect. The case describes the use and the effect of PTMA treatment. Safety and efficacy of the PTMA device will be investigated in the upcoming PTOLEMY 2 trial.