Prediction of ovulation by urinary hormone measurements with the home use ClearPlan® Fertility Monitor:: comparison with transvaginal ultrasound scans and serum hormone measurements
Prediction of ovulation by urinary hormone measurements with the home use ClearPlan® Fertility Monitor:: comparison with transvaginal ultrasound scans and serum hormone measurements
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DOI：
10.1093/humrep/15.12.2478
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发表时间：
2000-12-01
影响因子：
6.1
通讯作者：
Nieschlag, E
中科院分区：
文献类型：
--
作者：
Behre, HM;Kuhlage, J;Nieschlag, E
与排卵有关的性交时间强烈影响受孕的机会。每日血清LR测量或经阴道超声检查是不切实际的，以确定排卵在连续周期的个人。启动了一项前瞻性研究，以测试ClearPlan（R）生育监测仪（CPFM）在预测排卵方面的家用性能，并与经阴道超声检查和血清激素测量进行比较。共有53名年龄在18-39岁、子宫正常、至少有一个卵巢、周期长度在21-42天之间、未使用干扰卵巢功能的药物的妇女贡献了150个周期用于分析。一个周期是无排卵的，没有LH峰，表明生育高峰，由监测器检测到。在其余149个周期中，135个（90.6%）监测到LB激增，超声证实排卵。91.1%的周期在CPFM生育高峰期2天内排卵，51.1%的周期在LH峰后1天排卵，43.2%的周期在2天后排卵，CPFM生育高峰期或LH峰前无排卵。CPFM可以帮助那些希望怀孕的女性安排性交时间。它也可能有潜力作为诊断辅助和监测不孕症的治疗。
The timing of sexual intercourse in relation to ovulation strongly influences the chance of conception. Daily serum LR measurements or transvaginal ultrasonography are not practical to determine ovulation in consecutive cycles for an individual. A prospective study was initiated to test the home use performance of the ClearPlan(R) Fertility Monitor (CPFM) in ovulation prediction compared with transvaginal ultrasonography and serum hormone measurements. A total of 53 women aged 18-39 years with a normal uterus and at least one ovary, cycle length between 21-42 days and not using medication which interferes with ovarian function contributed 150 cycles for analysis. One cycle was anovulatory and no LH surge, indicating peak fertility, was detected by the monitor. Of the remaining 149 cycles, 135 (90.6%) had a monitor LB surge and ultrasonographically confirmed ovulation. Ovulation was detected in 91.1% of cycles during the 2 days of CPFM peak fertility, Ovulation was observed in 51.1% of cycles I day and in 43.2% of cycles 2 days after the surge in serum LH, Ovulation never occurred before CPFM peak fertility or the serum LH surge day. CPFM can help women who desire pregnancy to time intercourse. It may also have potential as a diagnostic aid and for monitoring the treatment of infertility.