Failure of selective termination and dexamethasone rescue therapy to arrest HELLP syndrome in a midtrimester triplet gestation with one triploid fetus
Failure of selective termination and dexamethasone rescue therapy to arrest HELLP syndrome in a midtrimester triplet gestation with one triploid fetus
复制标题
选择性终止妊娠和地塞米松抢救治疗未能阻止妊娠中期三胞胎妊娠（有一个三倍体胎儿）中的 HELLP 综合征
DOI：
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发表时间：
2005
影响因子：
1.8
通讯作者：
J. Jacob
中科院分区：
文献类型：
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作者：
N. Schwartz;B. Rochelson;J. Jacob
我们介绍了一名三胞胎妊娠患者的病例，该患者在 22 周时怀有一个三倍体胎儿 (69XXX)，该患者出现了严重的先兆子痫，且经地塞米松抢救治疗和选择性终止妊娠后并未逆转。随着多胎妊娠的增加，以及通过超声、血清标志物和侵入性手术对异常妊娠进行早期诊断，问题仍然存在：是否存在妊娠某个点，在此之前选择性终止异常胎儿可以使妊娠继续进行而不会出现先兆子痫或进展。在怀孕早期就 13 三体或三倍体病例的母体风险进行适当的咨询至关重要。
We present a case of a patient with a triplet pregnancy at 22 weeks with one triploid fetus (69XXX) who developed severe preeclampsia that did not reverse with dexamethasone rescue therapy and selective termination. With multiple gestations on the rise and the early diagnosis of abnormal pregnancies being accomplished through ultrasound, serum markers, and invasive procedures, the question remains if there is a point in gestation before which selective termination of an abnormal fetus would allow the pregnancy to continue without preeclampsia developing or progressing. Appropriate counseling as to the maternal risk in cases of trisomy 13 or triploidy is essential as early in pregnancy as possible.