Central neurocytoma responsive to topotecan, ifosfamide, carboplatin
Central neurocytoma responsive to topotecan, ifosfamide, carboplatin
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DOI：
10.1002/pbc.21551
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发表时间：
2008-07-01
影响因子：
3.2
通讯作者：
Wolff, Johannes E. A.
中科院分区：
文献类型：
--
作者：
Amini, Elharn;Roffidal, Tina;Wolff, Johannes E. A.
一个5岁的男性提出了脊髓下降转移从复发性神经细胞瘤。第1-3天给予拓扑替康（0.5 mg/m2）和卡铂（250 mg/m2），第1-5天给予异环磷酰胺（1，800 mg/m2），每21天一次，共3个周期，结果完全缓解，无严重并发症。文献回顾获得了20例中枢神经细胞瘤患者，但无完全缓解。中枢神经细胞瘤对化疗的完全反应仅在此报道，这对那些照顾这种罕见肿瘤患者的人有帮助。
A 5-year-old male presented with spinal cord drop metastasis from a recurrent neurocytoma. Topotecan (0.5 mg/m(2)) and carboplatin (250 mg/m(2)) were administered on days 1-3 and ifosfamide (1,800 mg/m(2)) on days 1-5, every 21 days, for three cycles and resulted in complete response without severe complications. A literature review yielded 20 patients with central neurocytoma but no complete responses. The complete response of central neurocytoma to chemotherapy only reported here should be helpful to those caring for patients with this rare turner.