Diagnosis and therapy of subclinically infected prostheses.
Diagnosis and therapy of subclinically infected prostheses.
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亚临床感染假体的诊断和治疗。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
D. H. Frank
中科院分区：
文献类型：
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作者：
C. Parsons;P. Stein;M. Dobke;C. Virden;D. H. Frank
我们认为，5%至7%的假体装置被表皮葡萄球菌“亚临床”感染。这些感染表现为慢性疼痛、移位和器械晚期挤出。为了研究这个问题，我们培养了阴茎和乳房假体。对于实验组，我们培养了由于症状（疼痛）而被移除的疼痛阴茎和乳房假体。对于对照组的患者，我们培养了由于机械故障（无疼痛）而被替换的阴茎假体和临时安装的乳房组织扩张器。在胰蛋白胨大豆肉汤中培养器械的实际部件。有14和12个疼痛的阴茎和乳房假体，分别有13和10个培养阳性，感染率为88%。鉴定的主要微生物为S。表皮无痛阴茎假体（5个假体中的0个和22个假体中的3个）生长S。表皮差异非常显著（p < 0.001），表明疼痛的假体受到感染。为了解决假体疼痛的问题，取出了10个假体并更换为新器械。患者在术前和术后接受抗生素治疗。所有10例均为阳性培养，10例中有9例成功交换（无疼痛）。
We believe 5 to 7 percent of prosthetic devices are "subclinically" infected by Staphylococcus epidermidis. These infections are manifested by chronic pain, migration and late extrusion of the devices. To examine this problem, we cultured penile and mammary prostheses. For the experimental arm, we cultured painful penile and mammary prostheses that were being removed because of symptoms (pain). For patients in a control group, we cultured penile prostheses being replaced because of mechanical failure (no pain) and mammary tissue expanders that were temporarily installed. Actual parts of the device were cultured in Trypticase Soy Broth. There were 14 and 12 painful penile and mammary prostheses, 13 and ten, respectively, were cultured positive, for an infection rate of 88 percent. The primary organism identified was S. epidermidis. The nonpainful penile prostheses (zero of five and three of 22 mammary prostheses) grew S. epidermidis. The differences were highly significant (p < 0.001), suggesting that the painful prosthesis is infected. In an attempt to resolve the problem of the painful prosthesis, ten prosthesis were removed and exchanged for new devices. Patients received preoperative and postoperative antibiotics. All ten had positive cultures and nine of ten were successfully exchanged (no pain).