Tough Triblock Copolymer Hydrogels with Different Micromorphologies for Medical and Sensory Materials
Tough Triblock Copolymer Hydrogels with Different Micromorphologies for Medical and Sensory Materials
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DOI：
10.1021/acsapm.9b00395
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发表时间：
2019-07
影响因子：
5
通讯作者：
Hui Jie Zhang;F. Luo;Y. Ye;T. Sun;Takayuki Nonoyama;T. Kurokawa;Tasuku Nakajima
中科院分区：
文献类型：
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作者：
Hui Jie Zhang;F. Luo;Y. Ye;T. Sun;Takayuki Nonoyama;T. Kurokawa;Tasuku Nakajima
采用新开发的“干燥和溶胀”方法，在不改变单体单元化学结构的情况下，构建了具有球形、圆柱形和片状微观结构的坚韧坚韧三嵌段共聚物水凝胶。这些坚韧三嵌段共聚物水凝胶通常表现出1000 MPa的高断裂应力，但根据其微观结构表现出不同的弹性模量。此外，所构建的层状凝胶在基础条件下形成pH敏感的光子凝胶，为凝胶应用提供了作为传感器的潜力。鉴于其高韧性，生物相容性和可调模量，这项研究有助于扩大两亲性嵌段共聚物水凝胶在医疗和工业用途中的潜在应用。
Tough triblock copolymer hydrogels with microstructures of sphere, cylinder, and laminae were constructed using a newly developed “drying and swelling” method without changing the chemical structures of their monomeric units. These tough triblock copolymer hydrogels commonly showed high fracture stress of ∼10 MPa but exhibited varied elastic moduli depending on their microstructures. Furthermore, the constructed laminar gel formed pH-sensitive photonic gel at the base conditions, providing the gel application with potential as a sensor. Given their high toughness, biocompatibility, and tunable modulus, this study helps expand the potential application of amphiphilic block copolymer hydrogels for medical and industrial use.