SYNCHRONIZATION OF HAPLOID YEAST-CELL CYCLES, A PRELUDE TO CONJUGATION
SYNCHRONIZATION OF HAPLOID YEAST-CELL CYCLES, A PRELUDE TO CONJUGATION
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DOI：
10.1016/0014-4827(73)90425-4
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发表时间：
1973-01-01
影响因子：
3.7
通讯作者：
HARTWELL, LH
中科院分区：
文献类型：
--
作者：
HARTWELL, LH
在细胞融合产生一个二倍体合子之前，酵母的非同步单倍体培养物需要与相反交配型的细胞进行一段时间的求偶。在这个求偶期发生的事件之一是两个单倍体细胞周期的同步，因为在融合时，两个细胞都是未出芽的单核细胞。这些结果与Bücking-Throm等人[4]假设的α因子在酵母交配过程中的作用一致。
Asynchronous haploid cultures ofSaccharomyces cerevisiaerequire an interval of courtship with cells of opposite mating type before cell fusion can occur to produce a single diploid zygote. One of the events occurring during this courtship period is the synchronization of the two haploid cell cycles, since, at the time of fusion, both cells are unbudded and mononucleate. These results are consistent with a role for α-factor in the yeast mating process as postulated by Bücking-Throm et al. [4].