Radioimmunoassay of IgE in middle ear effusions.
Radioimmunoassay of IgE in middle ear effusions.
复制标题
中耳积液中 IgE 的放射免疫分析。
作者：
G. Mogi;S. Maeda;T. Yoshida;N. Watanabe
使用最近开发的体外过敏测试放射性过敏吸附试验（RAST），研究了 56 对中耳积液样本和从中耳积液患者获得的血清，以了解针对螨虫的 IgE 抗体活性。 IgE 浓度也通过放射免疫吸附试验（RIST）测定。结果显示，在5份中耳积液和3份血清中发现了针对该过敏原的IgE抗体活性。 RAST 检测呈阳性的 5 名患者中有 4 名患有鼻过敏或提示过敏的体征。中耳有两处积液，似乎是过敏性液体。然而，本研究的结果并不表明中耳积液是由中耳腔粘膜内的螨虫引起的直接过敏反应引起的。
Fifty-six sample pairs of middle ear effusions and sera obtained from patients with otitis media with effusion were investigated for The IgE antibody activity against mites, using radioallergosorbent test (RAST) which was recently developed as an in vitro allergy test. The IgE concentrations were also determined by radioimmunosorbent test (RIST). Results showed that the IgE antibody activity against this allergen was found in 5 middle ear effusions and 3 sera. Four of 5 patients with the positive RAST test had nasal allergy or signs suggesting allergy. Theree were two middle ear effusions which seemed to be an allergic fluid. However, findings in the present study do not suggest that middle ear effusions result from the direct allergic reaction induced by mites in the mucous membrane lining the middle ear cavity.