Evaluation of macular changes before and after successful retinal detachment surgery using stratus-optical coherence tomography
Evaluation of macular changes before and after successful retinal detachment surgery using stratus-optical coherence tomography
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DOI：
10.1016/j.ajo.2006.01.080
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发表时间：
2006-07-01
影响因子：
4.2
通讯作者：
Brasseur, Gerard
中科院分区：
文献类型：
--
作者：
Lecleire-Collet, Amelie;Muraine, Marc;Brasseur, Gerard
目的：应用第三代光学相干断层扫描仪(Oct3)评价黄斑脱离视网膜脱离(maculate-off retinaldiscount，RD)手术前后黄斑的临床变化。设计：前瞻性观察队列研究。方法：对22例(22只眼)非连续黄斑视网膜脱离患者进行最佳矫正视力测量和OCT3黄斑中心凹扫描。分别采用Kruskal-Wallis多重比较检验和Mann Whitney U检验评价手术前后OCT黄斑特征、黄斑病变、黄斑中心凹脱离和最终视力(FVA)的关系。结果：术前视网膜内核层囊性空洞、术后黄斑轮廓异常、术后10月3日光感受器细胞内外段连接线缺失与FVA下降有关(分别为P=.001，P=10-4和P=0.015)。而术后黄斑中心凹脱离对FVA无明显影响(P=0.88)。结论：OCT3黄斑形态分析为了解黄斑脱离手术后视力不完全恢复提供了新的视角。
PURPOSE: To assess preoperative and postoperative infra, clinical macular changes in macula-off retinal detachment (RD) using third,generation optical coherence tomography (OCT3).DESIGN: Prospective observational cohort study.METHODS: Twenty-two nonconsecutive eyes of 22 patients with macula-off RD underwent best-corrected visual acuity measurement and OCT3 scans through the fovea before and after successful surgery. The relationship between preoperative and postoperative OCT macular char, acteristics, postoperative infra-clinical foveal detachment, and final visual acuity (FVA) were assessed using Kruskal-Wallis multiple comparison test and Mann Whitney U test, respectively.RESULTS: Preoperative cystic cavities in the inner nuclear layer of the detached retina, postoperative abnormal macular profile, and postoperative lack of the junction line between photoreceptor cell inner and outer segments on OCT3 were associated with a poorer FVA (P =.001, p = 10-4 and P =.015, respectively). In contrast, postoperative infra-clinical foveal detachment did not influence FVA (P =.88).CONCLUSIONS: Morphologic macular analysis using OCT3 provide some new insights to understand incomplete visual recovery after successful macula-off RD surgery.